An inducible caspase-3 "tumour death switch" model to identify circulating biomarkers of apoptotic cell death and test novel imaging probes for apoptosi
Abstract Purpose: Activation of the apoptotic cascade plays an important role in the response of tum...
Apical caspases initiate and effector caspases execute apoptosis. Reagents that can distinguish betw...
Background: The ability of living cells to respond appropriately to apoptosis signals is crucial for...
An inducible caspase-3 "tumour death switch" model to identify circulating biomarkers of apoptotic c...
Novel anticancer drugs targeting key apoptosis regulators have been developed and are undergoing cli...
Abstract Purpose We have previously developed the caspase-based radiotracer, 18F-ICMT-11, for PET im...
Apoptosis, or programmed cell death, is an essential physiological process that plays a critical rol...
Apoptosis is a highly regulated process involved in the normal organism development and homeostasis....
A newly developed system for the determination of Caspase 3 activity in individual apoptotic embryon...
Cell death plays a prominent role in the treatment of cancer, because most anticancer therapies act ...
Fluorescence lifetime imaging (FLIM) is a powerful imaging modality used to gather fluorescent repor...
Caspase-3 is a key mediator of apoptosis in mammalian cells. Cells expressing caspase-3 substrate pe...
Caspase‐3 is a proteolytic enzyme that functions as a key effector in apoptotic cell death. Determin...
In vivo imaging of apoptosis in a preclinical setting in anticancer drug development could provide r...
Caspases are proteases that play key role in the process of apoptosis, the programmed\ncell death. A...
Abstract Purpose: Activation of the apoptotic cascade plays an important role in the response of tum...
Apical caspases initiate and effector caspases execute apoptosis. Reagents that can distinguish betw...
Background: The ability of living cells to respond appropriately to apoptosis signals is crucial for...
An inducible caspase-3 "tumour death switch" model to identify circulating biomarkers of apoptotic c...
Novel anticancer drugs targeting key apoptosis regulators have been developed and are undergoing cli...
Abstract Purpose We have previously developed the caspase-based radiotracer, 18F-ICMT-11, for PET im...
Apoptosis, or programmed cell death, is an essential physiological process that plays a critical rol...
Apoptosis is a highly regulated process involved in the normal organism development and homeostasis....
A newly developed system for the determination of Caspase 3 activity in individual apoptotic embryon...
Cell death plays a prominent role in the treatment of cancer, because most anticancer therapies act ...
Fluorescence lifetime imaging (FLIM) is a powerful imaging modality used to gather fluorescent repor...
Caspase-3 is a key mediator of apoptosis in mammalian cells. Cells expressing caspase-3 substrate pe...
Caspase‐3 is a proteolytic enzyme that functions as a key effector in apoptotic cell death. Determin...
In vivo imaging of apoptosis in a preclinical setting in anticancer drug development could provide r...
Caspases are proteases that play key role in the process of apoptosis, the programmed\ncell death. A...
Abstract Purpose: Activation of the apoptotic cascade plays an important role in the response of tum...
Apical caspases initiate and effector caspases execute apoptosis. Reagents that can distinguish betw...
Background: The ability of living cells to respond appropriately to apoptosis signals is crucial for...